The dose may be repeated another 8 weeks, or up to 12 weeks if 25-hydroxyvitamin D levels are less than 30 nanograms/milliliter. The recommended dose of ergocalciferol in patients with vitamin D deficiency as a result of pregnancy, lactation, obesity, stage 2 chronic kidney disease, inadequate sun exposure, or supplementation, age older than 50 years, and primary or tertiary hyperparathyroidism is 50,000 international units orally every week for 8 to 12 weeks.
The optimal daily dose of vitamin D2 required to maintain serum calcium within normal limits without adverse effects ranged from 2.5 to 6.25 mg in 16 patients with either pseudohypoparathyroidism, idiopathic hypoparathyroidism, or postoperative hypoparathyroidism. Bone deformities improved in some patients with vitamin D2 therapy alone. High-dose vitamin D2 (50,000 to 300,000 international units daily) has been utilized in the treatment of vitamin D-resistant rickets in children and adults. Phosphorus and calcium homeostasis improved following long-term therapy with oral phosphorus 2 grams and vitamin D2 50,000 to 75,000 international units daily in patients with X-linked hypophosphatemic rickets and osteomalacia. Common adverse reactions include constipation, nausea, vomiting.Īdult Indications and Dosage FDA-Labeled Indications and Dosage (Adult) Familial x-linked hypophosphatemic vitamin D refractory rickets OverviewĮrgocalciferol is a bone density conservation agent that is FDA approved for the treatment of hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets, and familial hypophosphatemia. 
WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. Associate Editor(s)-in-Chief: Deepika Beereddy, MBBS Disclaimer
0 kommentar(er)
